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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: Comparative Transcriptomics Reveal Differential Expression of Coding and Non-Coding RNAs in Clinical Strains of Mycobacterium tuberculosis
doi: 10.3390/ijms26010217
Figure Lengend Snippet: ( A ) A Venn diagram showing significantly ( q < 0.05) differentially expressed sense ncRNAs in KZN vs. H37Rv and Beijing vs. H37Rv strains from Rockhopper Bioinformatics pipeline indicating shared and unique transcripts in each clinical strain compared to the laboratory strain. ( B ) A heatmap showing the expression patterns of 36 transcripts shared by all strains. The H37Rv strains exhibit higher expression of shared transcripts compared to other clinical strains and clustered closely to the Beijing strain. ( C ) The predicted ncRNA secondary structure of Transcript_130 with the predicted thermodynamic energy of −54.27 kcal/mol. ( D ) Transcript_130 exhibited a higher probability of interacting with the Rv2225 gene with thermodynamic energy of interaction −26.17 kcal/mol.
Article Snippet: 2.1.1.) software was used to map sequence reads against the M. tuberculosis H37Rv reference genome [ ] within
Techniques: Expressing